Don't let me discourage you from building your dream engine. I merely suggest you start with the best you can get and that's NOT the GM cast stuff. If you were building a daily driver with modest power maybe. For wanting to find out how far is too far and again what is the intended goal? Land speed record, 1/4 mile, hot rod? Hummer you want to keep original? Maybe you just want to know what is reasonable out of a stock GM cast block?
I will say for the money spent to wring power out of a 6.5 you could drop in ANY GM gas crate engine and buy the minor difference in gasoline with the pocket change. A Duramax is also a better choice in the quest for power. I will make the argument that a 6.5TD modified is a better engine than a LLY Duramax overheater.
Yes they all wear out, drop a valve, or otherwise die. I have had plenty of trouble with both.
You waste your time to lecture me on how reliable the 6.2/6.5 isn't. Start at post #8. GM Bean Counters thumbed their nose at Detroit Diesel's recommendations like use a forged crankshaft and later had to offer a 100K warranty on the 6.5 to sell them because of the 6.2 reputation for breaking the damn crankshaft in a horrible scrap metal death. Timing chain with 0.8" slop allowed, glow plugs and controllers that loved to kill engines, the cooling problems GM never figured out. Then the PMD pain.
A GM 6.2/6.5 fails you remove and replace it because it cracked to death. Block mains, cylinders, heads, precups... cracked to scrap. Odds ain't on the side of rebuilding. A Cummins fails you generally rebuild it including dropping a sleeve in it. Understanding the risk of hot oily parts sticking out of the pavement and having to start over when you start building power...
Additional pain is finding good parts anymore. From worn out head and rotors on Injection Pumps, injectors now made elsewhere and not the same quality, knock off or other parts no longer made to the original spec...
Oh yeah, when you want to get crazy with a Cummins they also make Forged Steel pistons that just laugh at a stuck open injector rather than melt down like aluminum pistons do.
4500RPM and then this happens.
" We had just crossed 2200HP at 146psi when the 6.7L Cummins block simply couldn't handle the pressure and separated! We have done over 3000HP on this longblock setup so we feel like it was definitely a premature failure... "
At the end of they day with 2000+ HP to "play with" that a 6.5 might make for 1/4 mile you are simply not going to make Cummins owners want a 6.5. After hopping up my 2003 5.9 Cummins, well, I have towed things at speed a 6.5 engine wouldn't dream of with power at lower RPM's... Having a warranty (on my 2018 RAM Cummins) for the same power my 2003 was at is a different world where I am no longer my own "warranty station".