If you go mechanical injection you wouldn't need the computer for that side of the equation. However if keeping the 4L80 you will need a standalone transmission controller to get the transmission to shift properly. I know there's older transmissions that didn't require computers. And the 92-93 4L80 behind the 6.5 were mechanical injection and had their own TCM, so if you could score a 92-93 4L80 w/ TCM that would work. Or go to a manual transmission and be computer free
If keeping the DS4, you'll definitely need to keep the ECM.