If not already present, gauges for fuel pressure and exhaust gas temperature (EGT) are your friends. Adding a boost gauge is also helpful.
With no real known history on the transmission, consider dropping some money here as well. If the tranny is 4L80E or 4L85E as designed by GM, it is arguably a weak link. Will do Ok for pushing, but not so great for slowing the load. Have not looked into alternatives recently, but there were outfits that did a good job at hardening the unit so that it can handle torque converter (TCC) lock-up for deceleration. If the budget allows, might want to look into a 6 speed transmission, but this will add some complexity.
Depending on who wrote the computer's logic (GM or Winnebago), it might need some adjustment as well. In the pickup truck platform, OE code wants to unlock the TCC under a lot of scenarios where the more seasoned driver wants it to remain locked to limit brake use. With a hardened tranny and code that keeps the TCC locked more than unlocked, speed control gets better.
Switching to a higher stall torque converter is known to help with both power and fuel economy as it allows the engine to more quickly jump above its lugging range and into its desirable sweet spot. Sweet spot will depend somewhat on the turbo.
Another thought on the OE code is that chances are good that it is not all that great at downshifting. Specifically, when climbing a grade with speed dropping, it will likely wait too long before commanding a downshift which lugs the engine, and leads to high exhaust temperatures along with diminished ability to shed heat. So when the time comes to adjust for better TCC lock-up, having notes on adjustments to shift behavior will help as well.
While on a brief tangent of heat control, when was the last time the fan clutch was changed? If unknown and it looks like it has a fair amount of age, consider replacement with new. Just be prepared to watch for a bad new unit.
Another cooling stack item is thermostat. An engine that is slow to warm, or wants to seemingly run cool on flat road at slower speeds, is indicating a stuck thermostat. All well and good on flat road when slow, but not your friend when looking to climb grade.
Am sure that by now the research has led down paths on how to get more power. One pathway to avoid is the marine injector. All it will do is make more smoke. I briefly drank that hype and was happier when I had an excuse to yank the marine injectors and go back to a good set of OE injectors. Only challenge that I am seeing with OE injectors is that finding a good set is not easy.
Toward power, best bets are to go after the low hanging fruit and stop there. Meaning, good path for air in, good path for exhaust out, and good fuel filtration / flow. Will already touched on the turbo.
If replacing fuel delivery components are necessary, if at all possible, pay extra for new injection pump (IP) and injectors. From experience, I have allergies to reman / rebuilt items.
Synthetic lubes will help with fuel economy.
Related to lubes, consider sending oil samples out for analysis. Some engine blocks have cracking issues and analysis will usually help identify this prior to needing a tow.
One last thought. Stick with OE spec glow plugs (GP) and DO NOT fall for the hype of the extra hot things. The OE spec GP is able to handle the alternator applying 14.X volts after engine start, the extra hot things can only handle nominal voltage (12.X volt range) and will self-destruct within the first 10K miles unless able to prevent the alternator from supplying current while the GPs are active.
For the future, have a set of ready plans when things break and need complete replacement. Failing to plan is planning to fail. This is an old platform with very thin support chain. Definitely not looking to scare, and am just offering some benefit from experience.