Well I'll talk about a Heath Cam. I have one in my engine now. After all the hard times getting the parts, under warranty, from Diesel Depot, I bought a 40K mile 1982 6.2l diesel, stuck a set of Celvite bearing on both sides of the connecting rods and both sides of the stock 6.2 crank shaft, bought a brand new set of 6.5 heads from Pennisular added a Heath towing cam and a GM-3 turbo. No problems, at all, at 63mph I get 17.5 miles per gallon. And that is with a 98 ex-cab 4x4 dually, 4L80E, 4:10's and 265x19.5 tires and wheels.
Well over 15k on the engine and no problems. With my car trailer, the total weight is about 13,000 and that gets me 12mpg. With the monster truck chassis on the trailer, and the trip, to Texas I got 10mpg.
How's that!