I'm in the process of doing this with my Blazer's R-12 system right now.
Change out the parts that are regular replacement items(Accumulator, Orifice tube). Also purchase the O-ring kit. you don't have to get one of those "200 piece o ring assortments. The kit i bought from advance auto was ~$6 and had all the o-rings i needed for my system.
Dip the O-rings in the oil you are going to use with the system before you install them. Since i'm using R-12 i'm using a mineral oil. With 134a you'll be using PAG oil.
Make sure you find out how much oil you have to add to the system. My compressor said "refrigerant oil - 10.0 oz". however only 6 of that 10 was in the compressor and the other 4 was to be distributed about the system. I poured 3 oz of oil in the evap top opening, and 1 oz of oil in the new accumulator, giving me the 10.0 of oil needed.
The accumulator is installed last as it has a desiccant in the bottom that's used to absorb moisture in the system. If you install that first and leave the system open to the air, that desiccant is going to try to absorb the moisture from the air, and it can't, so it becomes full and can no longer absorb moisture from the system once it's been closed again.
Once your certain that the rest of the system is all intact, install the new accumulator, making sure you use new O-rings with it. My ACDelco accumulator came with new o-rings but i used the ones that were in the o-ring kit as they looked to be better quality.
Now that the system has been sealed up, it's time to use your vac pump and gauges. Does your set of manifold gauges have a vacuum reading on the low side gauge? I know the old set I'm using does, and i'd figure most good quality ones will, but the cheapie's they sell at the auto parts chains do not.
Hook up the manifold gauges low gauge hose(blue hose) to the low side service port. Hook the yellow hose to the vac pump. Follow the procedures to start the vac pump after you check and make sure the oil(if it uses any) in the vac pump is full. Some you can just plug in and it's running. The one i'm using is oil-less so it's just plug in and go. Once the vac pump is running, open the low side gauge to the yellow hose by turning the hand wheel near the low side gauge. This will open the system to that yellow charging hose, and you should see the gauge start to read vacuum immediately. Mine dropped to 10 In of Hg instantly and continued to head towards 30 in of Hg. Once the gauge stops moving, close the hand wheel to isolate the A/C system again, and shut down the vac pump. Let it sit for 5 to 10 minutes while listening for leaks. If you've got a leak, the vacuum in the system will drop, and you'll see that on the gauge. If the needle doesn't drop after 10 or so minutes, re start the vac pump and re-open the hand wheel and let the vac pump run for at least 30 minutes. I let it run for about 45 and then let the vacuum sit in the system overnight to make sure it's not leaking at all, since R12 is not something you waste anymore considering how expensive it is.
Once you've run the vacuum for at least 30 minutes, close the system off again at the hand wheel, and shut down disconnect the vac pump. Your done with the vac pump so move it out of your way.
At this point you can start to charge the system. You can hook up the high side(red hose) if you haven't already, but do not open the hand wheel. The pressure in the high side line when the compressor is running(during charging) will cause the can to burst. You'll be using the high side gauge just to check for pressure in the system.
Hook up a can of refrigerant to the can tap but make sure the pin is all the way up into the can tap first. Tighten the can tap by hand. install the yellow hose onto the can tap. Now you'll want to pierce the can with the can tap once all the connections are tight. Rotate the can tap all the way until it's bottomed out. The can is pierced, and you cannot remove the can tap from it until the can is empty or the contents will be released to the air.
Open the low side hand wheel once again and then rotate the can tap so it's all the way up. Follow the instructions on the can for charging. Most can's say to rotate between 12 and 3 o clock while shaking the can. I just tend to rock the can back and forth from 12 to 3 and that works. Once the can feels empty most will say to hold it upside down for 1 minute to make sure it's empty. Once that's been done, close the low side hand wheel, close and remove the can tap from the yellow charging hose. remove the can tap from the now empty refrigerant can. you'll still get a slight hiss from any "empty" can, so don't worry about it.
Repeat the portion in blue above until you've installed the correct amount of refrigerant(go by weight listed somewhere on the system) and the pressures, both low and high, are in the correct zones.